IgG Food Antibodies Bloodspot by Genova Diagnostics Vs Intradermal Test

Food sensitivity testing has gained popularity in recent years as more and more people become aware of the potential impact that certain foods can have on their health. Among the various testing methods available, two that often come up in discussions are the IgG Food Antibodies Bloodspot Test by Genova Diagnostics and the Intradermal Test. In this article, we will explore these two tests in detail, comparing their benefits and drawbacks, to help you make an informed decision about which one may be right for you.

Understanding IgG Food Antibodies

Before delving into the specifics of the different tests, it is important to grasp the concept of IgG food antibodies. IgG, or immunoglobulin G, is an antibody found in our blood that plays a crucial role in our immune system's response to foreign substances, including food particles.

The Role of IgG in Food Sensitivity

Food sensitivity occurs when our bodies mistakenly identify certain foods as harmful and trigger an immune response, producing IgG antibodies to fight against them. This immune reaction can lead to a wide range of symptoms, such as digestive issues, skin problems, and even mood swings.

When we consume food, our immune system scans it for any potential threats. In the case of food sensitivity, the immune system overreacts and produces IgG antibodies as a defense mechanism. These antibodies bind to specific antigens present in the food, marking them as foreign invaders. This process sets off a cascade of reactions in the body, leading to the release of inflammatory chemicals and the manifestation of various symptoms.

How IgG Food Antibodies are Detected

The IgG Food Antibodies Bloodspot Test aims to identify specific foods that may be causing an immune response in your body by measuring the levels of IgG antibodies against various food antigens. This test can provide valuable insights into which foods you may be sensitive to and help guide dietary modifications to alleviate symptoms.

The test involves a simple bloodspot collection, where a small sample of blood is taken from a finger prick. The blood is then analyzed in a laboratory to measure the levels of IgG antibodies against a panel of food antigens. The panel typically includes a wide range of commonly consumed foods, such as dairy products, grains, fruits, vegetables, and meats.

Once the test results are obtained, they are interpreted by healthcare professionals who specialize in food sensitivities. The levels of IgG antibodies against each food antigen are analyzed, and a personalized report is generated. This report highlights the foods that elicited a significant immune response, categorizing them into different levels of reactivity.

Based on the test results, dietary modifications can be recommended to reduce exposure to reactive foods. This may involve eliminating or temporarily avoiding certain foods from your diet and gradually reintroducing them to assess tolerance. The goal is to reduce the burden on the immune system and alleviate symptoms associated with food sensitivity.

It is important to note that the IgG Food Antibodies Bloodspot Test is not a diagnostic tool for food allergies, which involve a different type of immune response mediated by IgE antibodies. Instead, it focuses on identifying food sensitivities, which are more commonly associated with delayed immune reactions and IgG antibodies.

By understanding the role of IgG food antibodies and how they are detected, individuals can gain valuable insights into their own immune responses to specific foods. This knowledge can empower them to make informed decisions about their diet and potentially improve their overall health and well-being.

An Overview of Genova Diagnostics' IgG Food Antibodies Bloodspot Test

The IgG Food Antibodies Bloodspot Test offered by Genova Diagnostics is a comprehensive and convenient method for assessing food sensitivities. This test requires only a small blood sample, which can be easily collected using a finger prick at home or in a healthcare professional's office.

The Science Behind the Bloodspot Test

The Bloodspot Test utilizes advanced laboratory techniques to measure IgG antibody levels. IgG antibodies are a type of immune response that can indicate food sensitivities. By analyzing the blood sample for reactivity against a panel of common food antigens, the test can identify specific foods that trigger an immune response in the body.

During the analysis process, the blood sample is carefully examined for IgG antibodies that bind to the food antigens. The levels of these antibodies are then quantified, providing valuable information about the severity of the immune response. This scientific approach ensures accurate and reliable results.

Interpreting the Results of the Bloodspot Test

Interpreting the results of the Bloodspot Test is crucial for identifying problem foods accurately. The test report categorizes the reactive foods into different sensitivity levels, ranging from mild to severe. This information allows you to prioritize the elimination or reduction of the most problematic items from your diet.

Understanding the severity of your sensitivities is essential for creating an effective dietary plan. The Bloodspot Test provides a detailed report that not only identifies the reactive foods but also indicates the level of sensitivity for each food. This allows you to make informed decisions about which foods to avoid or limit in order to manage your symptoms and improve your overall well-being.

Additionally, the test report may include recommendations for alternative food options or suggestions for further testing. This personalized guidance can be invaluable in navigating your dietary choices and optimizing your health.

It is important to note that the Bloodspot Test is not a diagnostic tool for food allergies, but rather a tool for identifying food sensitivities. Food sensitivities are different from allergies and often involve a delayed immune response. By identifying and managing these sensitivities, you can potentially alleviate symptoms such as bloating, fatigue, and digestive discomfort.

In conclusion, Genova Diagnostics' IgG Food Antibodies Bloodspot Test offers a convenient and comprehensive method for assessing food sensitivities. By utilizing advanced laboratory techniques, the test provides accurate and detailed results, allowing individuals to make informed decisions about their dietary choices. Understanding the severity of sensitivities and prioritizing the elimination or reduction of reactive foods can lead to improved overall well-being and symptom management.

Intradermal Testing for Food Sensitivity

Intradermal Testing is another approach commonly used to detect food sensitivities. This method involves injecting small amounts of food extracts into the skin and observing any localized immune reactions.

The Procedure of Intradermal Testing

During an Intradermal Test, a healthcare professional injects tiny amounts of various food antigens into the skin, typically on the forearm or back. Any subsequent reactions, such as redness or swelling, are closely monitored to identify potential food sensitivities.

Once the food extracts are injected, the immune system is stimulated, and the body's defense mechanisms come into play. The immune cells recognize the foreign substances and release chemicals that cause inflammation in the area. This localized immune response helps healthcare professionals determine if there is an underlying sensitivity to certain foods.

The process of injecting the food extracts is done using a fine needle to ensure precision and minimize discomfort. The healthcare professional carefully selects the specific food antigens based on the patient's medical history and suspected sensitivities. They may choose a variety of common allergens, such as peanuts, dairy, wheat, or shellfish, to cover a wide range of potential triggers.

Pros and Cons of Intradermal Testing

One advantage of Intradermal Testing is that it provides immediate results, allowing for timely decision-making regarding dietary adjustments. If a patient shows a strong reaction to a particular food antigen, they can eliminate it from their diet right away, potentially alleviating symptoms and improving their overall well-being.

However, it is worth noting that this test is more invasive than other methods of food sensitivity testing, such as blood tests. The injection of food extracts into the skin can cause temporary discomfort and may result in minor bruising or swelling at the injection site. Some individuals may find the procedure slightly painful, but the discomfort is usually short-lived.

Another consideration is that Intradermal Testing can sometimes yield false positive or negative results. False positives occur when a person shows a reaction to a food antigen but does not experience symptoms upon consumption. False negatives, on the other hand, happen when a person does not show a reaction during the test but later experiences symptoms after eating the specific food.

Furthermore, Intradermal Testing requires a visit to a healthcare professional's office for administration and monitoring. This means that individuals seeking this type of testing need to allocate time and resources for the procedure. Additionally, the test results should be interpreted by a qualified healthcare professional who can provide guidance and support in making dietary adjustments based on the findings.

Comparing the Bloodspot Test and Intradermal Test

Now that we have examined the basics of each test, let's compare the IgG Food Antibodies Bloodspot Test and Intradermal Testing in greater detail.

Accuracy and Reliability Comparison

The Bloodspot Test, being a blood-based test, offers a higher degree of accuracy and reliability compared to Intradermal Testing. The use of advanced laboratory techniques and precise measurements in the Bloodspot Test minimizes the risk of false results that can sometimes occur with Intradermal Testing.

Comfort and Convenience Comparison

When it comes to comfort and convenience, the Bloodspot Test is the clear winner. With the Bloodspot Test, you can collect the sample in the comfort of your own home, eliminating the need for a healthcare professional visit and any potential discomfort associated with the intradermal injection.

Making the Right Choice for Food Sensitivity Testing

When deciding between the IgG Food Antibodies Bloodspot Test and Intradermal Testing, several factors should be taken into consideration.

Factors to Consider When Choosing a Test

Consider your personal preferences, availability of healthcare professionals, and your comfort level with blood-based or skin-based testing methods. Also, evaluate the severity of your symptoms and the urgency of obtaining results when determining which test may be most suitable for you.

Expert Opinions on the Best Testing Method

It is always beneficial to consult with healthcare professionals or specialists who have experience in diagnosing and treating food sensitivities. They can provide tailored advice based on your individual circumstances and help guide you towards the most appropriate testing method.


In summary, the IgG Food Antibodies Bloodspot Test by Genova Diagnostics and Intradermal Testing are both valuable tools for identifying food sensitivities. However, each test has its own advantages and disadvantages.

The Bloodspot Test offers a comprehensive and convenient approach, providing accurate results with minimal invasiveness. On the other hand, Intradermal Testing offers immediate results, but it requires a visit to a healthcare professional's office and may yield false results.

Ultimately, the choice between the two tests depends on your personal preferences, symptoms, urgency for results, and guidance from healthcare professionals. It is advisable to consult with a knowledgeable healthcare provider who can help you determine the most suitable testing method for your specific needs.

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