Low FODMAP Digestive Enzymes: Which One to Choose (2026)
Short answer: Casa de Sante makes two low FODMAP enzyme products. Choose FODMAP Digestive Enzymes ($29.99) if beans, lentils, dairy or large, heavy meals are your triggers. Choose the 4-in-1 Enzymes + Prebiotics + Probiotics + Postbiotics ($29.89 for 60 capsules, 15 servings) if you also want daily probiotic support in the same capsule. Both were formulated by Onikepe Adegbola, MD, PhD, and both are third-party tested and made in a cGMP facility.
| Product |
Price |
Enzymes |
Also contains |
Best for |
| FODMAP Digestive Enzymes |
$29.99 |
Alpha-galactosidase (GOS in beans and legumes), lactase (lactose), carbohydrases for starch, proteases and lipases |
Nothing else |
Meals with beans, dairy, or a lot of protein and fat |
| 4-in-1 Enzymes + Prebiotics + Probiotics + Postbiotics |
$29.89 |
Alpha-galactosidase, cellulase, lactase, peptidase |
6 billion CFU Bacillus probiotics (DE111 B. subtilis, B. clausii), PreforPro prebiotic, S. cerevisiae postbiotic. No inulin or chicory root. |
People who want enzyme and microbiome support in one routine |
What enzymes cannot do
No enzyme product removes fructans from wheat, garlic or onion. Enzymes do not treat, cure or prevent IBS, SIBO or any disease, and they do not replace a low FODMAP elimination diet guided by a dietitian. Blood in the stool, weight loss, symptoms that wake you at night, or anemia need a doctor, not a supplement.
Compare brands: Best digestive enzymes for FODMAPs · Casa de Sante vs FODZYME. Product facts and prices last verified October 9, 2026.
