Is Licorice Root Extract Good for Acid Reflux? Benefits and Research

Acid reflux affects millions of people worldwide, causing uncomfortable symptoms like heartburn, regurgitation, and chest pain. While conventional medications offer relief, many individuals seek natural alternatives with fewer side effects. licorice root extract has emerged as a potential remedy for acid reflux symptoms, backed by both traditional use and modern research. This article explores whether licorice root extract is truly beneficial for acid reflux sufferers, examining the scientific evidence, potential benefits, and important considerations before use.

Understanding Acid Reflux

Acid reflux occurs when stomach acid flows back into the esophagus, the tube connecting your mouth and stomach. This backflow irritates the esophageal lining, causing the burning sensation known as heartburn. When these symptoms become chronic, occurring more than twice weekly, doctors may diagnose gastroesophageal reflux disease (GERD).

Common triggers include spicy foods, citrus, tomatoes, chocolate, caffeine, alcohol, and large meals. Lifestyle factors such as obesity, smoking, and stress can exacerbate symptoms. While proton pump inhibitors (PPIs) and antacids are standard treatments, their long-term use raises concerns about potential side effects, prompting interest in natural alternatives like licorice root.

The Impact of Acid Reflux on Quality of Life

Beyond physical discomfort, acid reflux can significantly impact quality of life. Chronic symptoms may disrupt sleep, affect eating habits, and cause anxiety around meals. Many sufferers report avoiding social dining situations and experiencing reduced productivity at work. The constant worry about triggering symptoms creates a cycle where stress worsens reflux, which in turn increases stress levels. This relationship between digestive health and overall wellbeing highlights why finding effective, gentle remedies is crucial for many patients.

What is Licorice Root?

Licorice (Glycyrrhiza glabra) is a flowering plant native to parts of Europe and Asia. Its root has been used medicinally for thousands of years across various cultures, including ancient Egyptian, Chinese, and Greek medicine. The sweet-tasting root contains numerous bioactive compounds, with glycyrrhizin being the most well-known.

Traditional uses of licorice root span respiratory conditions, digestive issues, and inflammatory disorders. Modern supplements typically use either whole licorice root or deglycyrrhizinated licorice (DGL), which has had the glycyrrhizin component removed to prevent certain side effects while maintaining therapeutic properties for digestive health.

Bioactive Compounds in Licorice Root

Licorice root contains over 300 compounds, many with potential health benefits. Besides glycyrrhizin, it contains flavonoids, isoflavones, chalcones, and coumarins that contribute to its anti-inflammatory, antimicrobial, and mucosal-protective effects. These compounds work synergistically to provide the therapeutic benefits associated with licorice. Research suggests these phytochemicals may help regulate immune response, protect cells from oxidative damage, and support the integrity of the digestive tract lining—all potentially beneficial for acid reflux sufferers.

Deglycyrrhizinated Licorice (DGL)

DGL is a specially processed form of licorice that has had the glycyrrhizin component removed. This modification is significant because glycyrrhizin, while medicinally active, can cause side effects like elevated blood pressure, reduced potassium levels, and fluid retention when consumed regularly. DGL retains the beneficial compounds for digestive health without these risks, making it the preferred form for treating acid reflux and other gastrointestinal issues. Most clinical studies on licorice for digestive health use DGL rather than whole licorice extract.

Scientific Evidence for Licorice Root and Acid Reflux

Research on licorice root for acid reflux shows promising results, though large-scale clinical trials are still limited. Several mechanisms may explain its potential benefits. Studies indicate that licorice compounds can increase mucus production in the stomach and esophagus, creating a protective barrier against stomach acid. This mucus coating helps defend the esophageal lining from acid damage.

Additionally, research suggests licorice has anti-inflammatory properties that may reduce inflammation in the esophagus caused by acid exposure. Some studies have found that DGL can inhibit the growth of H. pylori, a bacterium associated with peptic ulcers that can contribute to reflux symptoms in some individuals.

Clinical Studies and Research Findings

A 2012 study published in the Journal of Research in Medical Sciences found that a combination of licorice extract and other herbs significantly reduced symptoms in patients with functional dyspepsia, which shares some symptoms with GERD. Another study in the Evidence-Based Complementary and Alternative Medicine journal demonstrated that DGL, combined with other natural ingredients, improved quality of life scores in GERD patients compared to placebo.

Research from the World Journal of Gastroenterology suggests that licorice compounds may help heal damaged esophageal tissue by promoting cell regeneration and reducing oxidative stress. While these findings are encouraging, researchers emphasize the need for larger, more rigorous clinical trials specifically focused on licorice for GERD before definitive recommendations can be made.

Benefits of Licorice Root Extract for Acid Reflux

Based on available research and traditional use, licorice root extract may offer several benefits for those suffering from acid reflux. The mucus-stimulating effect creates a physical barrier that can reduce contact between stomach acid and the esophageal lining. This protective coating may provide relief from heartburn and reduce damage to esophageal tissue over time.

The anti-inflammatory properties of licorice compounds may help soothe irritated esophageal tissue and reduce the burning sensation associated with acid reflux. For some users, licorice provides a gentle alternative to conventional medications, potentially with fewer side effects when used appropriately, particularly in the DGL form.

Soothing Properties

Licorice root contains demulcent compounds that create a soothing coating over irritated tissues. This property makes it particularly valuable for esophageal irritation caused by acid reflux. The coating effect may provide immediate comfort while the anti-inflammatory compounds work to reduce underlying inflammation. Many users report a cooling, calming sensation after taking DGL supplements, which can provide welcome relief during acute reflux episodes.

Potential for Reduced Medication Dependence

For some individuals, incorporating licorice root extract into their reflux management plan may help reduce reliance on conventional medications. While PPIs and antacids are effective, concerns about long-term use have led many patients to seek complementary approaches. Some healthcare providers suggest DGL as part of an integrative approach, potentially allowing for lower doses of conventional medications. This strategy should always be discussed with a healthcare provider, as abruptly stopping prescribed medications can lead to rebound symptoms.

How to Use Licorice Root for Acid Reflux

DGL supplements are typically available as chewable tablets, capsules, powders, or tinctures. For acid reflux, chewable tablets are often recommended as they mix with saliva, which helps deliver the compounds directly to the esophagus. The typical dosage ranges from 200-600mg before meals and at bedtime, though this varies by product and individual needs.

For maximum benefit, most practitioners recommend taking DGL about 20-30 minutes before meals to allow the protective coating to form before food triggers acid production. Consistency is key—regular use tends to provide better results than occasional treatment. As with any supplement, it's important to choose high-quality products from reputable manufacturers to ensure potency and purity.

Licorice Root Tea Recipe for Acid Reflux

For those who prefer a soothing beverage approach, this low FODMAP licorice tea can provide gentle relief from acid reflux symptoms.

Soothing Licorice-Ginger Digestive Tea

A warming, gut-friendly tea that combines the soothing properties of DGL licorice with ginger's digestive benefits.

• 1 teaspoon DGL licorice root (not whole licorice)
• 1/2 teaspoon fresh ginger, sliced
• 1 small piece of lemon peel (optional)
• 1 cup water
• 1/2 teaspoon maple syrup (optional)

1. Bring water to a simmer in a small pot.
2. Add DGL licorice root, ginger, and lemon peel if using.
3. Reduce heat and simmer gently for 10 minutes.
4. Strain into a mug and add maple syrup if desired.
5. Drink 20 minutes before meals for best results.

Prep Time: 2 minutes

Cook Time: 10 minutes

Yield: 1 serving

Cuisine: Therapeutic

Precautions and Side Effects

While DGL is generally considered safe for most people when used appropriately, whole licorice extract containing glycyrrhizin can cause significant side effects with prolonged use. These include elevated blood pressure, reduced potassium levels, fluid retention, and hormonal effects. For this reason, DGL is the preferred form for acid reflux treatment.

Even with DGL, certain individuals should exercise caution. Pregnant and breastfeeding women should avoid licorice products. Those with hypertension, kidney disease, liver disease, or heart conditions should consult their healthcare provider before use. Licorice may interact with certain medications, including blood pressure medications, diuretics, and corticosteroids, so discussing potential interactions with your healthcare provider is essential.

Integrating Licorice with Other Digestive Supports

For comprehensive digestive health, many practitioners recommend combining licorice with other gut-supporting approaches. For those with sensitive digestive systems, pairing DGL supplements with low FODMAP certified products can provide additional relief. Casa de Sante offers a range of gut-friendly options, including digestive enzymes that can complement the action of licorice by supporting proper food breakdown and reducing the likelihood of acid reflux triggers.

Their prebiotic and probiotic supplements can further support overall gut health, addressing the gut microbiome imbalances that sometimes contribute to reflux symptoms. For those managing multiple digestive concerns alongside acid reflux, Casa de Sante's personalized meal plans offer a structured approach to identifying and avoiding trigger foods while ensuring nutritional adequacy—an important consideration when dietary modifications are needed for symptom management.

Conclusion

Licorice root extract, particularly in its deglycyrrhizinated form (DGL), shows promise as a complementary approach for managing acid reflux symptoms. Its ability to increase protective mucus, reduce inflammation, and soothe irritated tissues makes it an attractive option for those seeking natural remedies. While research results are encouraging, they remain preliminary, and larger clinical trials are needed to fully establish efficacy.

For those interested in trying licorice root extract for acid reflux, DGL supplements offer the safest approach. As with any complementary treatment, it's best used as part of a comprehensive management plan that includes appropriate dietary modifications, lifestyle changes, and medical supervision. Always consult with a healthcare provider before starting any new supplement, especially if you have existing health conditions or take medications. With proper use and realistic expectations, licorice root extract may provide valuable support for those navigating the challenges of acid reflux.