• The Advanced Microbiome Rebuilding Protocol by Casa de Sante
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casa de sante

The Advanced Microbiome Rebuilding Protocol

The Advanced Microbiome Rebuilding Protocol

$75.89 USD
$75.89 USD
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Shipping calculated at checkout.

Targeted support for rebuilding a resilient gut ecosystem. This MD PhD protocol combines a synbiotic (4.4 billion CFU probiotics plus the PreforPro® bacteriophage prebiotic, which is not a fiber) with low FODMAP digestive enzymes to foster a healthy microbiome.

Experience Optimum Gut Health 

Are you ready to revitalize your digestive health? Our Gut Health Bundle brings together two powerful supplements: Advanced Probiotic & Prebiotic and Our Low FODMAP Digestive Enzymes. All are designed to support a healthy gut and improve overall wellbeing.

Low FODMAP Advanced Probiotic & Prebiotic

Nourish your gut microbiota with our Advanced Probiotic & Prebiotic supplement. Low FODMAP, it's the perfect ally for those following a low FODMAP diet or anyone looking for a gut-friendly boost. This vegan, non-GMO supplement is free from gluten, dairy, and soy.
  • Probiotics help maintain a balanced gut flora, promoting a healthy digestive system and strengthening your immune response.
  • Prebiotics feed your beneficial bacteria, supporting their growth and activity.
Together, they work synergistically to support your gut health.

Low FODMAP Digestive Enzymes

Say goodbye to digestive discomfort with our Digestive Enzymes supplement. Also Low FODMAP, this product targets common digestive troubles like bloating, gas, and irregularity. By aiding the breakdown of food, it helps your body absorb nutrients more effectively, leading to improved overall digestion and energy levels.

Experience the power of our Gut Health Bundle today! Say yes to better digestion and greater overall well-being.

Evidence and quality: what backs this product

  • What is in the box (official, October 2026): 1 bottle Advanced Probiotic & Prebiotic synbiotic + 1 bottle FODMAP Digestive Enzymes. Bundle price $75.89; bought separately $75.98 ($45.99 + $29.99).
  • Advanced Probiotic & Prebiotic ($45.99 on its own), per the Supplement Facts label: PreforPro® 15 mg bacteriophage blend (LH01, LL5, T4D, LL12) plus 4.4 billion CFU of Bacillus subtilis DE111®, Bacillus coagulans, Lactobacillus acidophilus and Bifidobacterium lactis. 2 capsules daily, 30-day supply, preferably with meals.
  • Why no fiber: PreforPro® is a bacteriophage prebiotic used at 15 mg, not a fermentable fiber such as inulin, so it avoids the gas that large fiber doses cause in people with IBS.
  • FODMAP Digestive Enzymes ($29.99 on its own): alpha-galactosidase and lactase plus amylase, protease and lipase, taken with meals.
  • Third-party tested (independent lab verified) and made in a cGMP facility. Formulated by Onikepe Adegbola, MD, PhD (Dr. Onyx).

What this product cannot do

The enzymes target GOS (beans, legumes) and lactose. They do not break down fructans (wheat, onion, garlic) or polyols, so they do not replace a low FODMAP diet. Supplements do not diagnose, treat or cure IBS, SIBO or any disease; persistent bloating, weight loss, blood in stool or night-time symptoms need a clinician.

Frequently asked questions

What is in the Advanced Microbiome Rebuilding Protocol?

One bottle of the Advanced Probiotic & Prebiotic synbiotic and one bottle of FODMAP Digestive Enzymes.

How much does the bundle cost?

$75.89 on casadesante.com as of October 15, 2026. Bought separately the two products cost $75.98.

Does the prebiotic contain fiber or inulin?

No. The prebiotic is PreforPro®, a 15 mg bacteriophage blend, not a fermentable fiber.

How many CFU are in the probiotic?

4.4 billion CFU per serving from four strains, including the spore-forming Bacillus subtilis DE111®.

Do the enzymes work on onion, garlic or wheat?

No. The enzymes target GOS and lactose. They do not break down fructans or polyols.

Is it third-party tested?

Yes. Casa de Sante supplements are third-party tested by an independent lab and made in a cGMP facility.

Product details and price last verified October 15, 2026.

Shipping & Returns

US Orders: Shipping rates are calculated at order checkout. 

International Orders: Shipping calculated at checkout.

All orders placed before 12pm EST ship the same day.

Returns, Refunds and Exchanges

Our policy lasts 30 days. If 30 days have gone by since your purchase, unfortunately we can’t offer you a refund or exchange. To be eligible for a return, your item must be unopened (and uneaten) and in the same condition that you received it. It must also be in the original packaging. 

Please note, digital products are non refundable.

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NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”